GLPThree and Mature Hops (MH-3)

GLP THREE™ Spotlight Ingredient: MH3 (Think pHix))

Bitter-to-Vagus Signaling + Craving Pressure + “Post-Meal Calm” Support

(A unique gut→brain input that helps the system feel steadier—especially at snack o’clock.)

If MBC-267™ supports the “I’m satisfied” signal, and saffron supports the mood/craving loop, MH3 is the ingredient that brings something most people have never heard of—but often feel immediately when it’s working:

Bitter signaling.

MH3 isn’t “hops for hormones.”

It’s a mature hops bitter acids extract designed to deliver a meaningful bitter input to the gut—because bitter compounds aren’t just taste. They’re information.

And for weight management, that matters because the gut isn’t just digestion.

It’s a control center for appetite, stress signals, and nervous system state.

What MH3 is (think pHix)

MH3 is a concentrated extract from mature hops, standardized around bitter acids—with the emphasis on bitter.

Most people think “bitter” is just a flavor preference.

But biologically, bitter is a signal the body takes seriously.

When bitter receptors in the gut detect bitterness, it can influence:

• appetite-related signaling

• digestive rhythm and “settled stomach” cues

• autonomic balance (calm vs stressed)

• cravings and reward-driven snacking patterns

• thermogenesis pathways (how the body uses energy and produces heat)

  
  
  
  

So MH3’s role in GLP THREE™ is not to “stimulate.”

It’s to support a calmer, steadier gut-brain rhythm—so cravings and impulses don’t run the day.

Why MH3 matters for weight management

Midlife weight management is often less about “overeating at meals” and more about:

• stress eating

• grazing

• late-day snack pull

• feeling wired/tired

• feeling unsettled after meals

• “I’m not hungry but I want something”

  
  

Those patterns are heavily influenced by the gut–brain–vagus network.

And that’s where MH3 shines: it supports a “calmer metabolism” state—where appetite pressure, cravings, and nervous system reactivity are less likely to hijack choices.

The key concept: Gut → Vagus → Metabolism

Here’s the simplest way to understand MH3:

MH3 supports the signaling lane that helps your body shift out of “stressed + snacky” and into “settled + steady.”

When vagal tone and autonomic balance improve, people often experience:

• smoother digestion

• less stress-driven eating

• better “post-meal calm”

• less wired-tired energy

• fewer compulsive snack impulses

  
  

And that matters because a stressed nervous system will absolutely drive:

• sugar cravings

• salty cravings

• late-night reward eating

• “comfort snacking” even when you had enough food

What MH3 in GLP THREE™ is designed to support (primary benefits)

1) Reduced “snack attacks” (especially late-day / late-night)

The benefit: fewer impulsive snack urges.

Why it matters: this is where most plans fall apart.

Real-life outcomes people care about:

• less pantry wandering

• less “something sweet” after dinner

• fewer “I just need a little bite” moments that turn into a lot

What it feels like:

“The urgency is lower.”

2) Better “post-meal calm”

The benefit: meals feel more settling; less “still searching.”

Why it matters: if the body doesn’t feel settled after eating, it keeps scanning for more.

Real-life outcomes:

• fewer dessert impulses

• less grazing after meals

• more satisfaction and calm after eating

What it feels like:

“I ate… and I’m actually done.”

3) Autonomic balance support (calm metabolism)

The benefit: less reactive stress physiology.

Why it matters: stress pushes appetite behavior in the wrong direction—especially for women with heavy life load.

Real-life outcomes:

• less stress eating

• less comfort-food pull

• steadier appetite signals throughout the day

What it feels like:

“My system feels less braced.”

4) Thermogenesis / metabolic signaling support (subtle but important)

The benefit: supports energy utilization pathways the body uses for heat output and metabolic rhythm.

Why it matters: a “shut-down” stressed metabolism is often paired with cravings and fatigue.

Real-life outcomes:

• steadier daily rhythm

• fewer crashes

• less craving-driven eating because energy feels more stable

“Side benefits” people often love (beyond weight)

A) A calmer gut-brain relationship

Many women feel the connection between digestion and cravings:

• bloating → cravings

• stress gut → snack pull

• unsettled stomach → “I need something”

When that gut-brain lane feels steadier, choices feel easier.

B) Less wired-tired behavior

Women often describe being both exhausted and restless.

That state is a major driver of reward eating.

MH3 fits GLP THREE™ because it supports shifting toward a more settled baseline.

C) Better evening rhythm

Evenings are when cravings and “treat yourself” patterns spike.

MH3 is often easiest to explain as support for that late-day lane.

What it often feels like (real life)

People don’t say, “My vagal tone improved.”

They say things like:

• “I’m not snacking like I used to.”

• “My evenings feel calmer.”

• “I don’t have that same pull toward treats.”

• “After meals I feel more settled.”

• “The snack urgency turned down.”

That’s MH3’s signature: less pull.

MH3’s role in the GLP THREE™ system

In GLP THREE™, MH3 functions as the bitter-to-vagus lane—supporting the gut-brain rhythm that influences:

• craving pressure

• impulse snacking

• post-meal calm

• stress-driven appetite patterns

  
  

It’s one of the reasons GLP THREE™ feels like a “signal stack” instead of a diet trick—because it targets the nervous system side of appetite behavior.

The simplest way to explain it (out loud, in 10 seconds)

“MH3 is a bitter hops extract included to support gut-to-brain signaling—helping reduce snack attacks, support post-meal calm, and make cravings feel quieter, especially later in the day.”